This paper is Jean Frazier and David Kennedy's contribution to The Balanced Mind Foundation's series, Translation of the Scientific Evolution of Pediatric Bipolar Disorder.  The series presents the leading researchers' contribution to the field.  It describes the programmatic approach and direction of the labs, the seminal questions which drive their research, a listing of their most important findings and a summary of how their work impacts the field.   The Balanced Mind Foundation is very grateful to Drs. Frazier and Kennedy for sharing their vision with our readers.

Education, Medication, and More

A genetic test for bipolar disorder is on the horizon say researchers from Indiana University School of Medicine. 

The scientists published a “prototype” for laboratory testing in the online edition of the American Journal of Medical Genetics Part B: Neuropsychiatric Genetics.  (Read More)   

A family-based prevention program designed to help adolescents avoid substance use and other risky behavior proved especially effective for a group of young teens with a genetic risk factor contributing toward such behavior, according to a new study by researchers at the University of Georgia. The National Institute on Alcohol Abuse and Alcoholism (NIAAA) and the National Institute on Drug Abuse (NIDA), components of the National Institutes of Health, supported the study, which appears in the May/June issue of Child Development.

Did you miss our chat with Dr. Kiki Chang? Read the transcript of this exciting and informative chat. The Balanced Mind Foundation will be hosting several more expert chats this Fall. Watch your email for more details. 

Flipswitch is a fast-paced, fact-filled weekly podcast tackling issues such as wellness, stigma, and creativity. Join co-hosts Chris, Ryan, Gopi, and Emily each week for upbeat and informative segments such as 'Quizzo', '20 Facts in 120 Seconds', 'The 'X' Affect', 'Mood Disorders in the News', as well as interviews with the experts.

Dr. Hudziak is coauthor of one of the largest genetic studies looking at risk factors in children and youth. His research efforts have involved the study of genetic factors including social behaviors, obsessive-compulsive, attention, and aggressive behavior in boys and girls. 

The Flipswitch interview with Dr. Hudziak has been transcribed below.

This article stresses the interaction of genetic and environmental factors in the development of clinical depression.  Some individuals have a genetic tendency to place themselves in stressful experiences that activate their genetic predisposition to severe depression.Early life stress, such as neglect, abuse or early parental loss constitute major risk factors for depression.  Neuro- biological abnormalities are also found to be important factors in this development.

An interview with Dr. Kiki Chang about BP children with parents who have BP.  The article covers family history, symptoms and treatment.