Tag: early-onset bipolar

Impact of Early Onset Bipolar Disorder on Family Functioning

Research report that investigates the impact of adolescent onset bipolar illness on perceived family functioning. Author: Heather Robertson, et al

Efficacy of Lithium, Divalproex Sodium, and Carbamazepine in Children and Adolescents With Bipolar Disorder

by Kowatch, Robert A. M.D.; Suppes, Trisha M.D., Ph.D.; Carmody, Thomas J. Ph.D.; Bucci, John P. M.A.; Hume, Judith H. M.S.; Kromelis, Michelle R.PH.; Emslie, Graham J. M.D.; Weinberg, Warren A. M.D.; Rush, A. John M.D.

Journal of the American Academy of Child & Adolescent Psychiatry Copyright 2000 © American Academy of Child and Adolescent Psychiatry, Volume 39(6), June 2000, pp. 713-720

Objective: To develop effect sizes for 3 mood stabilizers-lithium, divalproex sodium, and carbamazepine-for the acute-phase treatment of bipolar I or II disorder, mixed or manic episode, in children and adolescents aged 8 to 18 years.
Method: Forty-two outpatients with a mean age of 11.4 years (20 with bipolar I disorder and 22 with bipolar II disorder) were randomly assigned to 6 weeks of open treatment with either lithium, divalproex sodium, or carbamazepine. The primary efficacy measures were the weekly Clinical Global Impression Improvement scores and the Young Mania Rating Scale (Y-MRS).